![]() ![]() ![]() CO is normally generated from the incomplete combustion of carbonaceous products 3. Further diagnostic markers mandates to be identified in order to avoid disputes in cases of extremely low COHb%-related poisoning.Ĭarbon monoxide (CO) is a colorless, odorless, non-irritant toxic gas which can cause harm to human body for its toxic effects ranging from cardiovascular and respiratory impairment to neuropsychiatric presentations and other acute complications 1, 2. In conclusion, CO poisoning with low COHb% significantly associates with fire circumstances and outdoor spaces and has no age preference. Five extremely low COHb% (< 30%)-related poisoning deaths were negative of any cardiopulmonary pathology and psychoactive substances. A combination with alcohol, but not other psychotropic drugs, associated with significant higher levels of blood COHb% in fire-unrelated ( p = 0.021) but not fire-related cases ( p = 0.23). Accordingly, group 1 was mostly related with fire burns, while group 2 or 3 were largely associated with gas leakage ( p = 0.00). 81.03% of group 1 cases died in fire circumstances, while only 45.57% from group 2 and 30.59% from group 3 were fire-related ( p = 0.00). ![]() All the CO poisoning from group 2 and 3 occurred in enclosed spaces, whereas cases from group 1 died additionally in outdoor spaces ( p = 0.01). Our results showed that group 2 and 3 were mostly observed in younger victims (≤ 30 years), while group 1 equally distributed to all age groups ( p = 0.03). Epidemiological, demographic, and forensic aspects of the CO poisoning cases, particularly those with low COHb levels, were analyzed. This study collected a total of 307 CO poisoning cases from Shanghai Public Security Bureau, an official organization that handles the most complicated and life-threatening cases across Shanghai municipality in China, and regrouped these cases into three categories: group 1, 10% < COHb% < 30% (n = 58) group 2, 30% ≤ COHb% < 50% (n = 79) group 3, COHb% ≥ 50% (n = 170). Features of the CO poisoning with low carboxyhemoglobin (COHb) levels remain to be characterized. Carbon monoxide (CO) poisoning is a common cause of death, leading to morbidity and mortality worldwide. ![]()
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